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Wednesday, May 21, 2008

Salmonella Virginia

Salmonella is actually a kind of bacteria, which invades the stomach and gut cells. Salmonella uses protein staples to hurt and restructure the gut cells of an effected person. Rockefeller team joined hands with the researchers of University of Virginia Health Science Center, and discovered that Salmonella bacteria injects protein cells into the guts of the host to create a structure of long filaments which can fold itself around this Salmonella bacterium.

This research helps to find out that how Salmonella bacterium affects intestinal track and gut cells and caused almost one billion new infections, all around the world, in a year. It has been noted that this bacteria cause more than 3 million deaths per year.

The process used by a Salmonella bacterium to enter into a host cell is considered to be one of the most intelligent and complex processes. When this bacterium wants to attack a host cell, it attaches with the host cell and use a syringe and needle to inject protein into the host cell. This protein, SipA, forced the proteins to joined together to make a filament, which changes the structure of the host cell.

The most commonly found Salmonella serotype in United States is Salmonella enterica serotype Typhimurium. According to the statistics this serotype caused 29 percent of the total infections caused by salmonella bacterium. Typhimurium is such a type of bacteria, which possesses and shows highest Antimicrobial resistance.The diseases and infection caused by Salmonella may last five to seven days and if the infection spread into the intestine, patients have to used antibiotics for treatment.

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